At nephrolithiasis stones are formed in renal pelvis or minor calyces. Stones irritate urinary tract, occlusion of their lumen leads to inflating by liquid and atrophy of renal tissue. If the infection joins, there is a pyelonephritis. Infection and stone formation are interconnected processes. Bacteria become a core of stones formation and the stones irritating walls facilitate penetration of bacteria.
The disease causes a megalgia (attack of renal colic) in loin, along ureter, in genitals. Pain arises at disturbance of urine passage because of occlusion with stone. It is followed by frequent urodynia, nausea, vomiting, and fever. At full ureteral occlusion the emiction is impossible. Often there are a blood and pus in urine.
Anesthetics can help to weaken the pain at renal colic. They are used in combination to drugs which take out spasm of unstriated muscles. It is prohibited to try “to wash it up” with plentiful drink without exact determination of stone location and sizes. Such attempts lead to jamming of the stone.
It is important to keep a diet with having excluded some foodstuff. For dissolution of stones medicines are offered, their application requires medical observation. Fine stones can leave after relief of renal colic. Excision of large stones requires a surgery. The perspective direction is a lithotripsy (crushing of stones with ultrasound).
Antibiotics, sulfanilamide, nitro furans are prescribed against infection.